Benefits of Melatonin

Within the world of natural health, melatonin continues to hold a strong presence due to its benefits in support of preventative health and wellness. Although most recognized for its aid in improving sleep, let it be known that the health indications for melatonin reach far beyond that of a simple night’s rest.


1. Melatonin and Cancer 

Melatonin proves beneficial in most cancers across the board, and studies also show that its co-administration improves the sensitivity of cancers to the anti cancer effects by conventional drugs and radiation. As important are the additional findings that melatonin can render cancers previously totally resistant to treatment sensitive once again to these same therapies. Although in most cases of illness and chronic disease, the continued repletion of deficient melatonin often creates its elicited effects, when it comes to cancer there is often a need for additional levels of melatonin beyond the average doses needed to treat most other diseases. 


2. Melatonin and Metabolic & Cardiovascular Disorders 

Metabolic syndrome has become increasingly more common. Associated with obesity, individuals who develop metabolic syndrome generally suffer from high levels of systemic inflammation. Metabolic syndrome is the co-presentation of several disorders (obesity, elevated lipids, and pre-diabetes or diabetes) that significantly increases the risk for heart disease, diabetes, and stroke. Research indicates that melatonin is a powerful antioxidant with the potential to greatly scavenge free radicals, which is often an underlying issue to this condition. In addition to its direct anti oxidative role, melatonin has also shown to have the potential to stimulate genes that promote antioxidant enzymes. Several studies have documented melatonin’s propensity to decrease an array of inflammatory mediators, all which are associated as an underlying influence in metabolic and cardiovascular disorders. 


3. Melatonin and Gastrointestinal Conditions  

Within the realm of gastrointestinal issues, there are many conditions which plague a large percentage of the population. From bloating and pain, heartburn to gas, the chronicity of gut related health issues are found to be responsive to melatonin. Irritable bowel syndrome (IBS), for example, is a common disorder characterized by recurrent abdominal pain or discomfort in combination with disturbed bowel habits in the absence of identifiable organic cause. Melatonin plays an important role in gastrointestinal physiology as it aids in the regulation of gastrointestinal motility, local anti-inflammatory reaction and moderation of visceral sensation. Science has shown melatonin can greatly improve IBS by its analgesic effects, regulation of gastrointestinal motility and its ability to affect the sensation to calm the gut in order to help promote better sleep. Other benefits of melatonin in gut health include its ability to help modulate gut microbiota, as a direct and potent anti-inflammatory, and its influence as a direct supporter of anatomical gut function.   


4. Melatonin and Other Health Conditions 

Although only a few highlights of melatonin have been explained here, rest assured that there are many more. Other conditions that can be greatly improved by melatonin include neurodegenerative conditions such as Alzheimer’s, Parkinson’s disease and dementia, mental disorders including schizophrenia, seasonal affective disorder, depression and anxiety, pain syndromes, a reproductive support, in traumatic CNS injuries, aging, infections, sleep issues as well as many others. 


Due to the beauty of how melatonin functions in the body, it is also astonishing that not only do supplemental doses rapidly improve many ill health conditions, chronic use of oral melatonin does not negatively affect its internal production. Supplemental melatonin often comes in common doses of 1mg to 5mg, however here at Signature Supplements, depending on its health indication, we have the capability to formulate much higher doses. Our leading edge in house compounding facility gives us the ability to utilize mini capsules, allowing us to pack very potent doses into extremely small and easy to swallow capsules! 


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